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The cost-effectiveness of a new chlorhexidine delivery system in the treatment of adult periodontitis

Article Abstract:

A chlorhexidine (CHX) chip placed in periodontal pockets following tooth scaling and root planing (SRP) may improve the treatment of periodontal disease, compared to SRP alone. SRP removes dead and infected tissue below the gumline and allows the gums to reattach to the tooth root in patients with severe gum disease. The CHX chip is a sustained-release antibiotic chip placed below the gum after SRP. Researchers compared the techniques in 416 patients. Additional maintenance procedures were required by 54% of patients treated by SRP alone and 46% who underwent SRP and received the CHX chip. The CHX chip improved gum healing without significantly increasing the cost of treatment.

Author: Jeffcoat, Marjorie K., Killoy, William J., Finkelman, Richard D., De Lissovoy, Gregory, Rentz, Anne M., Dukes, Ellen M., Eaton, Cheryl A.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 1999
Methods, Product/Service Evaluation, Surgery, Subgingival curettage, PerioChip (Medication)

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Assessing the effectiveness of locally delivered chlorhexidine in the treatment of periodontitis

Article Abstract:

Insertion of a dissolving chlorhexidine chip into periodontal pockets following root planing significantly reduces pocket depth, compared to planing alone. Advanced gum disease can cause the gum tissue to separate from the tooth root, leaving a pocket that accumulates bacteria and compromises the tooth and underlying bone. Researchers treated 565 patients with root scaling and planing, then inserted a chlorhexidine antibiotic chip or a placebo chip into the periodontal pocket. Half of the patients treated with a antibiotic chip achieved 2 mm or more reduction in pocket depth, compared to one-third of placebo-treated patients.

Author: Killoy, William J.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 1999
Drug therapy, Periodontal pockets

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An economic evaluation of a chlorhexidine chip for treating chronic periodontitis: the CHIP (Chlorhexidine in Periodontitis) study

Article Abstract:

Using a chlorhexidine chip to treat periodontal disease may be more expensive initially, but should result in fewer surgeries. In a study of 484 patients, those who were treated with scaling an root planing plus a chlorhexidine chip were 50% less likely to have surgery than those who were treated with scaling and root planing.

Author: Henke, Curtis J., Genco, Robert J., Killoy, William J., Miller, Dave P., Evans, Christopher J., Finkelman, Richard D.
Publisher: American Dental Association Publishers Inc.
Publication Name: Journal of the American Dental Association
Subject: Health
ISSN: 0002-8177
Year: 2001
Care and treatment, Economic aspects, Dental care, Oral hygiene

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Subjects list: Health aspects, United States, Evaluation, Chlorhexidine, Periodontal disease, Periodontal diseases
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