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The effect of bisoprolol on perioperative mortality and myocardial infarction in high-risk patients undergoing vascular surgery

Article Abstract:

The beta blocker bisoprolol appears to substantially reduce the risk of complications from vascular surgery in some patients. Vascular surgery is surgery performed on blood vessels. The surgery can cause heart attack in some patients who have risk factors for heart disease. Researchers randomly assigned 112 such patients to receive bisoprolol or standard care beginning one week before surgery and up to one month after. Only 3% of those taking bisoprolol had a heart attack or died from heart disease compared to 34% of those who received standard care.

Author: Boersma, Eric, Poldermans, Don, Bax, Jeroen J., Thomson, Ian R., Urk, Hero van, Blankensteijn, Jan D., Ven, Louis L.M. van de, Baars, Hubert F., Yo, Tik-Ien, Trocino, Giuseppe, Vigna, Carlo, Roelandt, Jos R.T.C.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Evaluation, Prevention, Heart attack, Blood vessels, Vascular surgery, Bisoprolol

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Predictors of Cardiac Events After Major Vascular Surgery: Role of Clinical Characteristics, Dobutamine Echocardiography, and [beta]-Blocker Therapy

Article Abstract:

People who have three or more risk factors for heart disease should have dobutamine stress echocardiography before they have any type of surgery. If this test reveals heart abnormalities, they should be treated for the heart condition before the surgery. People with few risk factors should be fine, especially if they take a beta-blocker before surgery.

Author: Boersma, Eric, Poldermans, Don, Bax, Jeroen J., Steyerberg, Ewout W., Thomson, Ian R., Banga, Jan D., Ven, Louis L. M. van den, Urk, Hero van, Roelandt, Jos R. T. C.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Usage, Cardiac patients, Heart function tests

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Levosimendan vs dobutamine for patients with acute decompensated heart failure

Article Abstract:

The effect of levosimendan and dobutamine on long term survival in patients with acute decompensated heart failure (ADHF) was studied. It was found that there was no difference in survival between patients with ADHF treated with levosimendan or dobutamine.

Author: Pocock, Stuart J., Packer, Milton, Nieminen, Markku S., Mebazaa, Alexandre, Cohen-Solal, Alain, Kleber, Franz X., Thakkar, Roopal, Padley, Robert J., Poder, Pentti, Kivikko, Matti
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
United States, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Congestive Heart Failure Preps, Drug therapy, Congestive heart failure, Dosage and administration, Congestive heart failure agents, Heart failure, Dobutamine, Clinical report

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Subjects list: Surgery
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