Effect of stimulatory and inhibitory drugs on uterine electrical activity measured noninvasively from the abdominal surface of pregnant rats

Article Abstract:

Measuring the electrical activity of the surface of the abdomen may be a good non-invasive substitute for measuring the electrical activity of the uterus, according to a study in rats. Doctors could use this method to analyze the activity of the uterus in women in premature labor.

Usage, Electromyography, Fetal monitoring, Diagnosis, Noninvasive, Noninvasive diagnosis

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Uterine activity during pregnancy and labor assessed by simultaneous recordings from the myometrium and abdominal surface in the rat

Article Abstract:

The electrical activity of the uterus at the end of pregnancy can be measured with electrodes on the abdomen. This could identify the start of labor. Researchers measured the electrical activity of the uterus in pregnant rats by placing electrodes on their abdomen and also on the surface of the uterus through an abdominal incisions. The electrical changes detected by the abdominal electrodes were smaller than those detected by the uterine electrodes, but they were similar in nature. Electrical activity changed substantially during the final 24 hours before delivery.

Labor (Obstetrics), Uterus, Uterine contractions, Myometrium

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The effect of chronic nitric oxide synthase inhibition on blood pressure and heart rate in unrestrained pregnant rats as recorded by radiotelemetry

Article Abstract:

Nitric oxide does not appear to be solely responsible for the changes in blood pressure during pregnancy. In a study on pregnant rats, inhibiting nitric oxide raised blood pressure temporarily, but blood pressure ultimately returned to normal. There may be other factors responsible for hypertension during pregnancy.

Nitric oxide, Hypertension in pregnancy, Gestational hypertension

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