Effects of 15 months of 17beta-estradiol and dydrogesterone on systolic cardiac function according to quantitative adn Doppler echocardiography in healthy postmenopausal women

Article Abstract:

Fifteen months of hormone therapy with 17beta-estradiol and dydrogesterone did not have any appreciable effect on the heart, according to a study of 30 healthy postmenopausal women who received this treatment or a placebo. The effect of hormone therapy on the heart is controversial, with some studies showing a beneficial effect and others showing no effect.

Heart

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The effects of 12 weeks of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis: A randomized, placebo-controlled, double-blind, dose-ranging study in healthy postmenopausal women

Article Abstract:

The short-term effects of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis are investigated. HMR 3339 and raloxifene decreased fibrinogen levels and in low dosage, HMR 3339 revealed potentially beneficial effects on some markers of fibrinolysis.

United States, Health aspects, Care and treatment, Estrogen, Estrogen receptors, Fibrinolysis, Blood diseases, Hematologic diseases

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Sequentially combined hormone replacement therapy reduces impedance to flow within the uterine and central retinal arteries in healthy postmenopausal women

Article Abstract:

Hormone replacement therapy appears to have beneficial effects on blood flow, which could explain why a lack of estrogen increases a woman's risk of cardiovascular disease. This was the conclusion of a study of 30 postmenopausal women, half of whom received hormone replacment therapy.

Blood flow

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