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The preterm prediction study: significance of vaginal infections

Article Abstract:

The presence of a bacterial vaginal infection at a certain point in pregnancy may be a risk factor for preterm labor and delivery. Researchers obtained vaginal specimens from 2929 women at either 24 or 28 weeks of pregnancy, and analyzed them for three different infectious organisms. Only the presence of bacterial vaginosis at 28 weeks' gestation was associated with preterm birth. Women with bacterial vaginosis at 28 weeks of pregnancy but not at 24 weeks were most at risk of delivering infants preterm. Risk factors for bacterial vaginosis were black race, young age, unmarried status, having several children, poverty, low educational level, and lack of private medical insurance.

Author: Goldenberg, Robert L., Das, Anita, Andrews, William W., Meis, Paul J., Iams, Jay D., McNellis, Donald, Mercer, Brian, Moawad, Atef, Thom, Elizabeth, Johnson, Francee
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
Complications and side effects, Risk factors, Premature birth

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Time course of the regression of asymptomatic bacterial vaginosis in pregnancy with and without treatment

Article Abstract:

A study is conducted on 658 women with asymptomatic bacterial vaginosis to determine the time course of the regression of asymptomatic bacterial vaginosis in pregnancy with and without treatment and the probability of spontaneous resolution with placebo. Women undergoing placebo treatment had a significant remission of bacterial vaginosis over ten weeks and the remission is more common when the initial vaginal microbiologic disturbance is less.

Author: Carey, J. Christopher, Hauth, John C., Sibai, Baha M., Miodovnik, Menachem, Iams, Jay D., Dombrowski, Mitchell P., Moawad, Atef, Wapner, Ronald J., MacPherson, Cora A., Klebanoff, Mark A, Heine, R. Phillips, vanDorsten, J. Peter
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
United States, Science & research, Care and treatment, Research, Lactobacillus, Metronidazole, Bacterial vaginosis

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Benefits of maternal corticosteroid therapy in infants weighing 1,000 or less grams at birth after preterm rupture of the amnion

Article Abstract:

Giving pregnant women corticosteroids when their membranes rupture prematurely does not appear to be beneficial. Corticosteroids are often given to prevent some complications of premature birth but a study of 214 premature babies revealed no significant benefit from corticosteroids.

Author: Hauth, John C., Moawad, Atef H., Iams, Jay D., Thurnau, Gary R., Sibai, Baha, Thom, Elizabeth, Bottoms, Sidney F., Chapman, Shelley J.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
Evaluation, Drug therapy, Corticosteroids, Adrenocortical hormones, Premature labor

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Subjects list: Vaginosis
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