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The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: implications for the future health burden and population screening

Article Abstract:

The study showed that there was a high prevalence of carriers of alpha thalassaemia (8.53%), beta thalassaemia (2.54%), and both alpha and beta thalassaemia (0.26%) in the Guangdong Province of China. The details obtained from this study enabled the projected number of pregnancies at risk to be estimated and a screening strategy to be designed for the control of thalassaemia in this area.

Author: Xu, X.M., Zhou, Y.Q., Liao, C., Luo, G.X., Zhou, M., Chen, P.Y., Lu, J.P., Jia, S.Q., Xiao, G.F., Shen, X., Li, J., Chen, H.P., Xia, Y.Y., Wen, Y.X., Mo, Q.H., Li, W.D., Li, Y.Y., Zhuo, L.W., Wang, Z.Q., Chen, Y.J., Qin, C.H., Zhong, M.
Publisher: British Medical Association
Publication Name: Journal of Clinical Pathology
Subject: Health
ISSN: 0021-9746
Year: 2004
China, Health aspects, Control, Thalassemia, Beta thalassemia

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COX-2 dependent PGE2 downregulates alpha integrin expression via the EP3 receptor in cultured mesangial cells

Article Abstract:

A study is made to find whether the effect mediated by prostaglandin E2(PGE2) acting throyugh its EP2 receptor in cultured rat mesangial cells. It is seen in glomerulonephritis, cyclooxygenase 2 (COX-2) appears to suppress the expression of alpha integrins by the increased production of prostaglandin E2 activating its EP3 receptor.

Author: Waldner, C., Schror, K., Heering, P.
Publisher: British Medical Association
Publication Name: Journal of Clinical Pathology
Subject: Health
ISSN: 0021-9746
Year: 2004
United States, COX-2 inhibitors, Glomerulonephritis, Synthetic prostaglandins E

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Tenascin C expression is upregulated in pancreatic cancer and correlates with differentiation

Article Abstract:

Author: Juuti, A., Nordling, S., Louhimo, J., Lundin, J., Haglund, C.
Publisher: British Medical Association
Publication Name: Journal of Clinical Pathology
Subject: Health
ISSN: 0021-9746
Year: 2004
Finland, Evaluation, Measurement, Prognosis, Glycoproteins, Pancreatic cancer

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