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The primary prevention of coronary heart disease in women

Article Abstract:

Primary means of reducing the risk of coronary heart disease in women include not smoking, lowering total cholesterol levels, engaging in physical activity, and treating high blood pressure and obesity. Women who smoke have 2 to 4 times the risk of coronary heart disease than women who do not. Decreasing levels of low-density lipoprotein and increasing levels of high-density lipoprotein reduce the risk. Women who are physically active may have 60% to 70% lower risk than inactive women. Moderate alcohol intake, antioxidant vitamins, and aspirin may also lower the risk. The use of oral contraceptives, sudden and early menopause, and removal of the ovaries increase the risk. However, normal menopause does not suddenly increase risk. Hormone replacement following menopause may help reduce risk, but may not benefit other aspects of women's health. Studies have shown that treating serious hypertension reduces CHD risk, however treating mild hypertension may not. Diabetes mellitus increases the risk of death from coronary heart disease by 3 to 7 times in women.

Author: Hennekens, Charles H., Buring, Julie E., Manson, Joann E., Rich-Edwards, Janet W.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1995
Women, Prevention, Coronary heart disease, Diseases

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Comparison of self-reported diagnosis of connective tissue disease with medical records in female health professionals: the Women's Health Cohort Study

Article Abstract:

Self-reported diagnosis of connective tissue disease has been compared with medical records for female health professionals in the Women's Health Cohort Study. Subjects were selected from 395,543 women who reported CTD, some with and some without breast implants. Then 220 with the implants and who also self-reported CTD and a random sample of CTD reporters without the implants were matched by age and date of diagnosis. Confirmation on rates of definite CRD were similar in the implant and nonimplant subjects, but the study showed difficulty of obtaining consent for medical record review of CTD reported to have occurred years ago in these women.

Author: Hennekens, Charles H., Buring, Julie E., Manson, Joann E., Lee, I-Min, Cook, Nancy R., Karlson, Elizabeth W.
Publisher: Johns Hopkins University Press
Publication Name: American Journal of Epidemiology
Subject: Health
ISSN: 0002-9262
Year: 1999
United States, Statistical Data Included, Research, Methods, Usage, Diagnosis, Medical personnel, Health surveys, Connective tissue diseases, Breast implants, Epidemiological research, Cross sectional studies, Experimental design, Research design, Medical statistics, Questionnaires, Statistics (Mathematics)

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Adjunctive drug therapy of acute myocardial infarction - evidence from clinical trials

Article Abstract:

Certain drugs could reduce mortality rates in people who have a heart attack. Studies have shown that the most effective drugs are beta blockers and ACE inhibitors. These drugs should be given to all patients with heart attack in addition to thrombolytic drugs to break up blood clots and aspirin to prevent blood clots. ACE inhibitors should be given for several weeks and beta blockers for several years. Calcium channel blockers, lidocaine, antiarrhythmic drugs and magnesium have not been proven effective in many trials.

Author: Hennekens, Charles H., Buring, Julie E., Albert, Christine M., Gaziano, J. Michael, Godfried, Susan L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Drug therapy, ACE inhibitors, Angiotensin converting enzyme inhibitors, Heart attack, Adrenergic beta blockers, Adrenergic beta-antagonists, Magnesium, Magnesium (Metal), Calcium channel blockers, Anti-arrhythmia drugs, Antiarrhythmia agents

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Subjects list: Health aspects
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