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A dual function for CD40 agonists

Article Abstract:

Research shows that agonistic antibodies against CD40 can be used in treating chronic autoimmune inflammatory diseases. Issues include use of CD40 as a mediator against invaders and cancer cells, which provides a protective and therapeutic immunity 'in vivo.'

Author: Zanelli, E., Toes, R.E.M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Cancer cells, Cell research, Cytological research

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Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic inflammatory process

Article Abstract:

Research on agonistic monoclonal antibodies used against CD40 is presented. These antibodies may be used to boost the immune system, and fight infectious agents and chronic diseases, such as arthritis and cancer.

Author: Mauri, Claudia, Mars, Lennart T., Londei, Marco
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
United Kingdom, Monoclonal antibodies

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Probing for prions: recognizing misfolded PrP

Article Abstract:

Paramithiotis et al. introduce a set of new antibodies that selectively recognize the putative transmissible spongiform encephalopathies (TSE) pathogen. The description of this new called (PrP) is illustrated.

Author: Caughey, Byron
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2003
Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Research and Testing Services, Medical Research, Epilepsy & Muscle Disease R&D, Administration of Public Health Programs, Health Research Programs, Prions, Prions (Proteins), Viral antibodies, Medicine, Experimental

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Subjects list: Research, United States, Analysis, Physiological aspects, Chronic diseases, Medical research, Autoimmune diseases, Antibodies
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