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Transfusion strategies for patients in pediatric intensive care units

Article Abstract:

A noninferiority trial was conducted on 637 stable, severely ill children with hemoglobin concentration less than 9.5g per deciliter after being admitted in an intensive care unit for seven days to determine that a restrictive transfusion strategy of using packed red cells that were leukocyte-reduced before storage is as safe as a liberal transfusion strategy. It was inferred that the transfusion requirements were reduced without increasing adverse results in children with a hemoglobin threshold of 7 g per deciliter for red-cell transfusion.

Author: Collet, Jean-Paul, Ducruet, Thierry, Lacroix, Jacques, Tucci, Marisa, Joffe, Ari, Hebert, Paul C., Hutchison, James S., Gauvin, France, Hume, Heather A., Tolendano, Baruch J., Robillard, Pierre, Biarent, Dominique, Meert, Kathleen, Peters, Mark J.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Science & research, Research, Blood transfusion, Pediatric intensive care, Critically ill children, Clinical report

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Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review

Article Abstract:

Lowering body temperature can reduce the risk of death and neurological complications in people with a traumatic brain injury, particularly if it is continued for 24 hours and the body is re-warmed within 24 hours. This was the conclusion of researchers who analyzed 12 clinical trials of induced hypothermia. However, they still consider this an experimental treatment.

Author: Moher, David, Hebert, Paul C., McIntyre, Lauralyn A., Fergusson, Dean A., Hutchison, James S.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Evaluation, Brain injuries, Hypothermia, Induced, Induced hypothermia

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Promotion of Breastfeeding Intervention Trial (PROBIT): A Randomized Trial in the Republic of Belarus

Article Abstract:

Breast feeding reduces the risk of gastrointestinal illness and allergic diseases in babies, according to a study of 16,491 mothers and their newborn babies. Half the mothers were encouraged to breastfed their babies as much as possible and the other half were not.

Author: Kramer, Michael S., Chalmers, Beverley, Hodnett, Ellen D., Sevkovskaya, Zinaida, Dzikovich, Irina, Shapiro, Stanley, Collet, Jean-Paul, Vanilovich, Irina, Mezen, Irina, Ducruet, Thierry, Shishoko, George, Zubovich, Vyacheslav, Mkunik, Dimitri, Gluchanina, Elena, Dombrovskiy, Viktor, Ustinovitch, Anatoly, Kot, Tamara, Bogdanovich, Natalia, Ovchinikova, Lydia, Helsing, Elisabet
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Health aspects, Prevention, Food and nutrition, Infants (Newborn), Newborn infants, Allergy, Breast feeding

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Subjects list: Care and treatment
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