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Transient relapses ("Blips") of plasma HIV RNA levels during HAART are associated with drug resistance

Article Abstract:

The authors discuss what they call "blips," occasional brief rises of viral load in HIV-positive patients who are receiving HAART. They determined that the "blips" involve drug-resistant HIV, the implication of which is that viral replication continues to occur during HAART therapy. The "blips" do not seem to interfere with long-term success in suppressing viral replication.

Author: Stuart, James WT Cohen, Wensing, Annemarie MJ, Kovacs, Colin, Righardt, Maike, de Jong, Dorien, Kaye, Steve, Schuurman, Rob, Visser, Corjan JT, Boucher, Charles AB
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
United Kingdom, Canada, Netherlands, Physiological aspects, HIV patients, Drug resistance in microorganisms, Microbial drug resistance, Highly active antiretroviral therapy

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Influence of preassay and sequence variations on viral load determination by a multiplex real-time reverse transcriptase-polymerase chain reaction for felline immunodeficiency virus

Article Abstract:

Researchers evaluate a reverse transcriptase polymerase chain reaction test to measure the amount of feline immunodeficiency virus in blood samples from infected cats. They were able to detect many different strains from clade A using two different primer/probe systems.

Author: Hofmann-Lehmann, Regina, Klein, Dieter, Leutenegger, Christian M., Bahula, Claudia, Gold, Peter, Salmons, Brian, Lutz, Hans, Gunzburg, Walter H.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
Polymerase chain reaction, Feline immunodeficiency virus

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Early detection of reverse transcriptase activity in plasma of neonates infected with HIV-1: a comparative analysis with RNA-based and DNA-based testing using polymerase chain reaction

Article Abstract:

A supersensitive reverse transcriptase assay called Amp-RT is more effective than nucleic acid sequence-based amplification and DNA-PCR in detecting HIV infection in newborn babies. This was the conclusion of a study of 71 babies.

Author: Folks, Thomas M., Heneine, Walid, Reisler, Ronald B., Thea, Donald M., Pliner, Vadim, Green, Timothy, Lee, Francis, Nesheim, Stephen, Brown, Teresa, Kalish, Marcia
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
Diagnosis, HIV infection in children, Pediatric HIV infections

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Subjects list: Usage, Measurement, Viremia, Viral load
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