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Transmission of West Nile virus from an organ donor to four transplant recipients

Article Abstract:

Suspicion of transmission of West Nile virus through organ transplantation is reviewed by identification of associated blood components in persons who donated blood to the organ donor. It is concluded that organ recipients receiving immunosuppressive drugs may be at high risk for severe disease after West Nile virus infection with blood transfusion being the probable source of the West Nile virus viremia in the organ donor.

Author: Chamberland, Mary E., Winquist, Andrea G., Peterson, Lyle R., Goodman, Jesse L., Perlino, Carl A., Marfin, Anthony A., Lanciotti, Robert S., Pham, Si M., Iwamoto, Martha, Hellinger, Walter C., DiazGranados, Carlos A., Jernigan, Daniel B., Guasch, Antonio, Zaki, Sherif, Trepka, Mary Jo, Wiersma, Steven, Blackmore, Carina G., Lance-Parker, Susan E., Hillyer, Krista L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Science & research, Care and treatment, Research, Organ transplant recipients, Organ donors, Tissue donors

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West Nile virus among blood donors in the United States, 2003 and 2004

Article Abstract:

Data from the West Nile virus program of the American Red Cross for 2003 and 2004 to identify geographic and temporal trends is analyzed. Rapid implementation of a nucleic acid amplification test led to the perspective identification of 519 donors who were positive for West Nile virus RNA and the removal of more than 1000 potentially infectious related components from the blood supply of the Red Cross.

Author: Stramer, Susan L., Dodd, Roger Y., Chyang T. Fang, Foster, Gregory A., Wagner, Annette G., Brodsky, Jaye P.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United States, Risk factors, Blood donors, Blood donation

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Subjects list: West Nile virus
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