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Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women

Article Abstract:

In a study of 85,941 women aged 34 and 59 years and with no previous history of coronary heart disease or cancer, the incidence of heart disease was reduced by 21% due to diet and lifestyle changes. Dietary improvement, smoking reduction, and increased hormone therapy were associated with 9-16% reductions in heart disease incidences, but overweight was associated with an 8% increase in the disease

Author: Willett, Walter C., Stampfer, Meir J., Hu, Frank B., Manson, Joann E., Grodstein, Francine, Colditz, Graham A., Speizer, Frank E.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
United States, Statistical Data Included, Analysis, Evaluation, Demographic aspects, Coronary heart disease, Diet, Diet in disease, Disease susceptibility

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Postmenopausal estrogen and progestin use and the risk of cardiovascular disease

Article Abstract:

Adding progestins to estrogen as hormone replacement therapy in postmenopausal women does not appear to reduce the protective effect of this treatment against cardiovascular disease. This has been demonstrated in the Nurses Health Study, which has followed 59,337 women since 1976. As of 1992, 770 women had developed heart disease and 572 had had a stroke. Progestin and estrogen use lowered the risk of cardiovascular disease 60% and estrogen alone lowered the risk 40%. Neither hormone appeared to reduce the risk of stroke.

Author: Willett, Walter C., Hennekens, Charles H., Stampfer, Meir J., Manson, Joann E., Grodstein, Francine, Colditz, Graham A., Speizer, Frank E., Rosner, Bernard
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Cardiovascular diseases, Prevention, Postmenopausal women, Estrogen, Estrogens, Progestational hormones

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A prospective study of risk factors for pulmonary embolism in women

Article Abstract:

Certain risk factors appear to increase a woman's risk of developing a pulmonary embolism. Pulmonary embolism occurs when a blood clot forms in one part of the body and travels to the lungs. Among the 112,822 women in the Nurses' Health Study, there were 280 cases of pulmonary embolism. Obese women had 3 times the risk of pulmonary embolism and heavy smokers had 2 to 3 times the risk depending on how many cigarettes they smoked per day. High blood pressure also increased the risk by a factor of 2 while blood cholesterol levels and diabetes appeared to play no role in pulmonary embolism.

Author: Willett, Walter C., Hennekens, Charles H., Stampfer, Meir J., Manson, Joann E., Grodstein, Francine, Colditz, Graham A., Speizer, Frank E., Goldhaber, Samuel Z.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Hypertension, Risk factors, Pulmonary embolism

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Subjects list: Health aspects, Obesity, Smoking, Hormone therapy
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