Trends in zidovudine prescription for pregnant women infected with HIV

Article Abstract:

Zidovudine prescriptions have become more common among HIV-infected pregnant women. Researchers studied 714 women with HIV infection and pregnancy from 1990 to 1996. Among women with the lowest CD4+ T-cell counts, 82% had been given zidovudine throughout the study period. Prescriptions for women with higher CD4+ counts showed a trend toward more use of the antiviral drug. Prescription rates rose from 22% to 55% among women with CD4+ counts of 500 cell/micro-L or greater from 1990 to 1996. Zidovudine can reduce the risk of transmitting HIV to the infant during pregnancy and childbirth.

Prevention, HIV infection in children, Pediatric HIV infections, Disease transmission, Pregnancy, Zidovudine, HIV infection in pregnancy

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Surveillance for thrombocytopenia in persons infected with HIV: results from the multistate adult and adolescent spectrum of disease project

Article Abstract:

Thrombocytopenia appears to occur with increasing frequency as AIDS progresses and is associated with increased mortality. Thrombocytopenia is a drop in blood platelets, which help form blood clots. Analysis of the medical records of 30,214 HIV-infected patients revealed that 8.7% of those with AIDS had thrombocytopenia compared to 3% of those with a low T cell count but not AIDS and only 1.7% of those with neither condition. Thrombocytopenia significantly shortened survival even after adjusting for other complications of HIV infection.

Complications and side effects, HIV infection, Thrombocytopenia

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Geographic differences in noninjection and injection substance use among HIV-seropositive men who have sex with men: western United States versus other regions

Article Abstract:

The use and abuse of alcohol and drugs by HIV-positive men who have sex with men (MSM) varies by racial or ethnic groups and from one region of the United States to another. HIV-positive MSM tend toward high use of drugs and alcohol in general. Using a mostly Hispanic group as a reference point, interviews with 9,735 MSM revealed whites as significantly more likely to report use of hallucinogens, marijuana, nitrites, amphetamines (not injected) and diazepam. Black MSM were more likely to report use of crack cocaine.

Demographic aspects, HIV patients, Drug use, Drug abuse

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