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Single-dose antibiotic prophylaxis for patients undergoing extended pelvic surgery for gynecological malignancy

Article Abstract:

There is an increased risk of infection following extensive pelvic surgery. The incidence of infection following prophylactic single and multiple doses of antibiotics was studied among 116 patients before surgery to treat gynecological cancer. Patients were given a single dose of antibiotic administered in the operating room 45 minutes before surgery. Additional doses were given 8 and 16 hours later. Two types of hysterectomies were performed. There was no difference between the overall surgical site infection rate with either operation type (4.3 and 4.5 percent) or antibiotic treatment schedule. Patients that developed a hospital-acquired infection were more likely to have had hospital stays of longer than 10 days. A single dose of antibiotics was effective in reducing the risk of infection after extended pelvic surgery for the treatment of gynecological cancer. (Consumer Summary produced by Reliance Medical Information, Inc.)

Author: Patsner, Bruce, Orr, James W., Jr., Sisson, Pamela F., Barrett, Jeffrey M., Ellington, John R., Jr., Jennings, Ralph Henry, Jr., Paredes, Keith B., Taylor, Dale L., Soong, Seng Jaw, Roe, Cathy
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1990
Evaluation, Antibiotics, Prevention, Surgery, Surgical wound infections, Postoperative complications, Cancer, Cross infection

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Incisional bowel herniations after operative laparoscopy: a series of nineteen cases and review of the literature

Article Abstract:

The use of large surgical openings during laparoscopy may lead to hernias after surgery at the incision sites. Researchers evaluated records of laparoscopic surgeries at various hospitals to determine the rate of bowel herniations at incision sites. Twenty-one bowel herniations in 19 patients occurred. The total number of laparoscopic surgeries could not be determined. Herniations may develop in both umbilical and non-umbilical incision sites. The risk of herniations may increase when surgical openings are 10 millimeters or more in size, when screws are used to anchor the opening to the abdominal wall, and when surgeons overuse the opening. Smaller instruments and close follow-up of patients may reduce the rate of complications.

Author: Spirtos, Nick M., Orr, James W., Jr., Boike, Guy M., Miller, Charles E., Mercer, Lane J., Fowler, Jffrey M., Summitt, Robert
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1995
Causes of, Hernia, Laparoscopy

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Subjects list: Complications and side effects
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