Vascular endothelial growth (VEGF) induces remodeling and enhances T(sub H)2-mediated sensitization and inflammation in the lung

Article Abstract:

Exaggerated levels of vascular endothelial growth factor (VEGF) are present in persons with asthma, but their role in normal and asthmatic lungs are not defined and hence an experiment was conducted by generating lung-targeted transgenic mice to evaluate its role in T-helper type 2 cell (T(sub H)2)-mediated inflammation. The results reveal that VEGF regulation may be therapeutic in asthma and other T(sub H)2 disorders.

Asthma, Vascular endothelial growth factor

---

Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants

Article Abstract:

The role of circulating lymphatic endothelial progenitors in de novo lymphangiogenesis in human renal transplants is examined. A stepwise mechanism of inflammation-associated de novo lymphangiogenesis is observed involving potential lymphatic progenitor cells derived from the circulation, transmigrated through the connective tissue stroma and incorporated into the growing lymphatic vessel.

Science & research, Lymphatic vessels, Renal replacement therapy

---

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

Article Abstract:

Research presented concerns the impact of poly(ADP-ribose) polymerase (PARP) activation on endothelial dysfunction in diabetics. Treatment of diabetic mice with a PARP inhibitor shows promise in maintaining vascular health, despite the continuance of severe hyperglycemia.

Statistical Data Included, Physiological aspects, Development and progression, Diabetics, Peripheral vascular diseases, Endothelium, Cytology, DNA polymerases

Similar abstracts:

• Abstracts: Bacterial meningitis: recent advances in pathophysiology and treatment. Evidence of Zoonotic Transmission of Cryptococcus neoformans from a Pet Cockatoo to an Immunocompromised Patient
• Abstracts: Placental corticotropin-releasing hormone: function and regulation. Changes in salivary estriol increases before parturition at term
• Abstracts: Acceleration of fetal head induced by vibration of maternal abdominal wall in sheep. Thyrotropin-releasing hormone: does two hundred micrograms provide effective stimulation to the preterm fetal pituitary gland compared with four hundred micrograms?
• Abstracts: Long-term postmenopausal hormone use, obesity, and fat distribution in older women. Hormone Replacement Therapy and Cognition: Systematic Review and Meta-analysis
• Abstracts: Ulcerative colitis and colorectal disease: a population-based study. Appendectomy and protection against ulcerative colitis

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.