Endogenous bacterial receptors should cause anxiety

Article Abstract:

The discovery of gamma-aminobutyric acid and benzodiazepine bacterial binding sites indicated the possibility of the presence of other bacterial neurotransmitter receptors. This creates uncertainty in studies involving bacterial expression systems because of the existence of other endogenous bacterial receptors. However, additional experiments may provide better understanding of these binding sites.

Physiological aspects, Bacteria, Binding sites (Biochemistry), Active sites (Biochemistry), Neurotransmitters, Benzodiazepines, Drug receptors

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Channel-linked receptors - from subunits to novel drug targets

Article Abstract:

New perspectives from the Symposium on Neuronal Ligand-gated Ion Channels as Drug Targets, held at the 15th Helsinki University Congress of Drug Research, June 10-11, 1999, are discussed. Topics include the modulation of GABA(sub A)-receptor function, a gene-targeted approach to anxiety, glycine receptors, and the therapeutic potential of AMPA and kainate receptors.

Finland, Analysis, Conferences, meetings and seminars, Genetic aspects, Ion channels, Anxiety, Drug targeting

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