Towards a revised nomenclature for P1 and P2 receptors

Article Abstract:

Differences in pharmacological properties and transduction mechanisms has led to issues concerning the classification and nomenclature of adenosine receptors (P1) and purinoceptors (P2). Proof that adenosine triphosphate operates through two distinct transduction mechanisms and developments in purinoceptor cloning stress the need to classify purinoceptors into G protein-coupled receptors and intrinsic ion channels. Revision of the nomenclature of the receptors, however, remains difficult since classification by pharmacologists are based on the receptor's structure.

Names, Cell receptors, Adenosine triphosphate, ATP

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Dopamine receptors in the caudate nucleus and memory processes

Article Abstract:

Evidences from studies aimed to analyze the human memory process reveal that dopamine D2 receptors in the posteroventral or ventrolateral regions of the caudate nucleus are involved in the consolidation of memory. Rats which have been conditioned and injected with D-amphetamines responded to stimulus providing evidences of memory retention. Results supported the role of dopamine D2 receptors in memory processing in specialized regions of the brain.

Memory, Dopamine receptors, Caudate nucleus

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Cysteinyl leukotriene receptors in the human lung: what's new?

Article Abstract:

Previous studies have shown that leukotrienes play a crucial role in the mechanics of asthma allergy. Two cysteinyl leukotriene receptors, namely, CysLT1 and CystLT2, have been identified as sites for leukotriene reaction. However, the precise identification of the types of receptor responsible for mediating relaxation and contraction has yet to be achieved. New pharmacological tools are needed to explore and classify these receptors.

Physiological aspects, Asthma, Leukotrienes

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