Antisense has growing pains
Article Abstract:
Many scientists are concerned that clinical trials of antisense drugs are premature. Evidence is accumulating that the compounds do not work in the body as researchers had believed. Others argue that, as long as the drugs seem to help, clinical trials should continue.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
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Backup gene may help muscles help themselves
Article Abstract:
Researchers a trying a new approach to a genetic therapy for Duchenne type muscular dystrophy. They are attempting to use the utrophin gene to stimulate the production of a muscle-strengthening protein to replace the dystrophin that patients are unable to make.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
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Antisense aims for a renaissance
Article Abstract:
Interest in antisense therapies is reviving following promising clinical trials for antisense drugs for cancer, AIDS and Crohn's disease. Antisense firms are developing a second generation of drugs that avoid the problems of earlier antisense drugs.
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
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