Evaluation of liposome-water partitioning of organic acids and bases. 1. Development of a sorption model

Article Abstract:

Researchers from Switzerland and the U.S. presented a model to describe the experimental data from liposome-water distribution ratios using equilibrium dialysis.

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Evaluation of liposome-waterpartitioning of organic acids and bases. 2. comparison of experimental determination methods

Article Abstract:

Researchers from Switzerland and the U.S. compared three assay methods used in the evaluation of liposome-water partition coefficients of organic acids and bases using equilibrium dialysis.

Acid-base chemistry

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Partitioning of substituted phenols in liposome-water, biomembrane-water, and octanol-water systems

Article Abstract:

Twenty chloro- and nitrophenols with varied acidities and hydrophobicities were analyzed to assess the effects of pH, ionic strength and compound concentration on the sorption of phenolic compounds to liposomes and to chromatophores. It was found that for many environmentally relevant phenols, the membrane-water partitioning at ambient pH values is substantially affected by the sorption of the phenoxide, not by the partitioning of the neutral species as assumed.

Cyclic crudes and intermediates, Cyclic Crude and Intermediate Manufacturing, Phenol, Analysis, Phenols, Phenols (Class of compounds), Membranes (Biology), Phenol (Compound)

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