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Homing in on a prostate cancer gene

Article Abstract:

An international research team has against all odds identified a gene as a risk factor for hereditary prostate cancer, on chromosome 1. There is some indication that the gene may be a cancer-promoting oncogene rather than a tumor suppressor gene, which becomes a risk factor when mutated.

Author: Pennisis, Elizabeth
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Genetic aspects, Prostate cancer

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Behavioral effects and gene delivery in a rat model of Parkinson's disease

Article Abstract:

Reduced apomorphine-induced turning behavior in rats may not be a good criterion of dopaminergic action on striatal neurons. Reduced turning can result from damage to the neostriatum caused by viral infusions used to deliver the L-dopa synthesizing enzyme.

Author: During, Matthew J., Isacson, Ole, Geller, Alfred I., Naegele, Janice R., O'Malley, Karen L.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Drug therapy, Drug delivery systems, Parkinson's disease, Parkinson disease

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The chameleon within: improving antigen delivery

Article Abstract:

Researchers have determined a method for converting the epithelial cells lining the intestine into a type of M cells, which can transport antigens into the immune system. The finding may lead to methods for increasing the efficiency of oral vaccination.

Author: Madara, James L.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Epithelial cells, Antigens, Oral vaccines

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Subjects list: Research
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