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New knockout mice point to molecular basis of memory

Article Abstract:

A new limited knockout mouse, in which a gene coding for a neurotransmitter receptor was deleted only from a small group of cells in the hippocampus, helped identify molecular changes responsible for memory. The experiments examine memory processes from molecular changes to neuronal misfiring to impaired learning.

Author: Roush, Wade
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Psychological aspects, Innovations, Memory, Brain research, Genetically modified mice

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New lesion found in diseased brains

Article Abstract:

Research has uncovered a third type of brain lesion in Alzheimer's patients. Dubbed 'AMY plaques' because they were misidentified as amyloid plaques, these lesions are as prevalent as plaques that contain B-amyloid protein and could play a role in causing the disease.

Author: Roush, Wade
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Research, Alzheimer's disease, Brain diseases

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