Unraveling the mechanisms involved in motor neuron degeneration in ALS
Article Abstract:
The proposed mechanisms involved in the amyotrophic lateral sclerosis (ALS), the reasons why motor neurons are a key target in the disease and how other cell types could contribute to the disease are reviewed. Though there is no effective remedy for this fatal disorder, modern genetics has now identified mutations in Cu/Zn superoxide dismustace (SODI) gene as primary cause for the disease.
Publication Name: Annual Review of Neuroscience
Subject: Science and technology
ISSN: 0147-006X
Year: 2004
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Pain mechanisms: labeled lines versus convergence in central processing
Article Abstract:
A study was conducted showing new perspective that views pain in humans as a homeostatic emotion that integrates both specific labeled lines and convergent somatic activity. It targets the issue of whether pain is represented by specific neural elements or by patterned activity within a convergent somatosensory subsystem.
Publication Name: Annual Review of Neuroscience
Subject: Science and technology
ISSN: 0147-006X
Year: 2003
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