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Releasing the brakes on antitumor immune response

Article Abstract:

Recent research showed promise of cancer immunotherapy based on inhibiting counter-regulatory receptors for T-Cell receptors, thus removing the natural limits to the body's immune response. Antibodies for counterreceptor CTLA-4 injected into cancerous mice enabled a T-cell response to succeed.

Author: Pardoll, Drew
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Care and treatment, Cancer, Cancer treatment, T cell antigen receptors, T cells, Immune response, Immunotherapy

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Genetic models for studying cancer susceptibility

Article Abstract:

Research on the micromelanophores of platyfish and swordtails provide clues to the genetic nature of cancer susceptibility. Research indicates that several genes are responsible for susceptibility to melanoma.

Author: Friend, Stephen
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1993
Melanoma, Disease susceptibility

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Subjects list: Research
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