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Receptor mutations help slow disease progression

Article Abstract:

A research team led by Stephen O'Brien has discovered evidence that people with two mutant copies of the CCR5 gene are resistant to AIDS infection and that AIDS progression is slower in patients with one mutant copy. CCR5 is a chemokine receptor used by HIV to infect white cells.

Author: Cohen, Jon
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Research, Development and progression, HIV infection, HIV infections, Genetic aspects, AIDS (Disease), O'Brien, Stephen

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New hope against blindness

Article Abstract:

Early human trials indicate that local administration of ganciclovir, foscarnet and HPMPC may be effective in treating cytomegalovirus, a herpes virus that causes vision problems including blindness in as many as 40% of patients in the final stages of AIDS.

Author: Cohen, Jon
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Drug therapy, AIDS patients, Cytomegalovirus infections, Dosage and administration, Ganciclovir, Foscarnet

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Please pass the data

Article Abstract:

Scientists complain that the European Union and Japanese projects on sequencing the Arabidopsis, or mustard plant, are not sharing their sequences with US researchers. Similar complaints about Japanese rice genome studies surfaced in 1994.

Author: Cohen, Jon
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
International aspects, Political aspects, Science and state, Science policy, Chromosome mapping

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