Structure of gene-tag protein solved

Article Abstract:

Green fluorescent protein (GFP), taken from the Pacific Northwest jellyfish, has been used as a fluorescent marker in molecular biology studies. Recent discoveries of the structure of normal and mutant GFP may allow researchers to alter the protein, such as making new colors for multi-marker studies.

Equipment and supplies, Genetic aspects, X-ray crystallography, Bioluminescence

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Structure of cytochrome c oxidase, energy generator of aerobic life

Article Abstract:

A research team has completed an x-ray analysis of three dimensional crystals of cytochrome c oxidase, a membrane protein that acts to conserve energy in the respiratory process. The discovery focuses on the structure of the metal-containing sites in the enzyme.

Cover Story, Physiological aspects, Metalloenzymes

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Mammalian cytochrome c oxidase, a molecular monster subdued

Article Abstract:

Researchers have analyzed the complete structure of bovine cytochrome c oxidase at 2.8 angstroms. The enzyme has 13 separate subunits and a molecular weight of 200,000, making it the most complex membrane protein to be analyzed at high resolution.

Analysis

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