Effect of aging on circadian rhythm of atrial natriuretic peptide, plasma renin activity and plasma aldosterone

Article Abstract:

The effect of aging on the circadian rhythm of atrial natriuretic peptide, plasma renin activity and plasma aldosterone and plasma cortisol levels was studied. There was an increase of 24-hour mean plasma levels for elderly subjects aged 65 to 75 yearsold. However, the circadian rhythm for atrial natriuretic peptide was not significantly different between the two age groups. The divergent changes in atrial natriuretic peptide and plasma renin activity in elderly subjects suggest that atrial natriuretic peptide exerts a counterregulatory role on the tonic phase of renin.

Aldosterone assay, Natriuretic peptides, Aldosterone, Renin

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Model systems for studying aging

Article Abstract:

The various model systems foraging have their own features to answer different hypotheses in a study. The lineage-specific cells in longterm culture may provide insights in growth control. Single-celled organisms or simple invertebrates may also be used because of their relatively short life spans, limited dietary needs and geneticmalleability. Mammals may be used to compare cells either in situ in young and old individuals as well as tested in cultures after removal from the organism.

Analysis, Biological models

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Aging and cancer - another perspective

Article Abstract:

The relationship between the incidence the high incidenceof cancer among the elderly and process of aging was explored. Recent animal studies had only confounded reseachers as more of senescence related processes are continuously being uncovered. The role of the immune system had been found to be irrelevant, however, aging rate and the pathophysiology of cancer were found to have a genetic basis.

Editorial, Evaluation, Demographic aspects, Genetic aspects, Immunity, Immunity (Physiology), Carcinogenesis, Age factors in disease, Disease age factors

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