Growth hormone: fountain of youth or death hormone?

Article Abstract:

Studies have shown that in older people growth hormone will increase muscle mass, but not strength. Exercise is more effective for increasing muscle strength and is not enhanced by growth hormone, which has adverse effects and may be life-shortening. Supplementation with growth hormone in healthy older people is not justified based on current knowledge. In severely ill, malnourished elderly it may be useful. More study is needed.

Editorial, Practice, Somatotropin, Geriatrics, Insulin-like growth factor 1, Insulin-like growth factor I

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Risk factors relating blood markers of inflammation and nutritional status to survival in cachectic geriatric patients in a randomized clinical trial

Article Abstract:

The effect of proinflammatory cytokines, their receptors, and nutritional indicators upon long-term survival in geriatric cachetic patients without active acute infections, inflammation, or cancer is evaluated. The results indicate that in geriatric weight-loss patients with cachexia, certain cytokines and nutritional indicators are effective in predicting long-term mortality, regardless of treatment with megestrol acetate.

Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Research and Testing Services, Geriatric Research, Research, Cytokines

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Improvement in quality-of-life measures and stimulation of weight gain after treatment with megestrol acetate oral suspension in geriatric cachexia: results of a double-blind, placebo-controlled study

Article Abstract:

Treatment of geriatric cachexia with megestrol acetate oral suspension has been studied using a 12-week double-blind, placebo-controlled study. Improvement in quality-of-life measures and stimulation of weight gain were seen three months after treatment. Weight loss is a common clinical problem in older patients.

Statistics, Demographic aspects, Quality of life, Weight loss, Appetite, Appetite (Psychophysiology), Nursing home patients, Megestrol acetate, Megestrol

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