The association between vascular risk factor-mediating medications and cognition and dementia diagnosis in a community-based sample of African-Americans

Article Abstract:

Vascular risk factor-mediating medications and cognition and dementia diagnosis have been studied in a community-based sample of 2,212 African-Americans. Use of the medications, especially antihypertensives, seems to be helpful in cutting risk of cognitive impairment in older subjects. Caution is in order in prescribing antihypertensives with centrally acting sympatholytic properties to older patients.

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The role of antihypertensive agents in preventing cognitive impairment

Article Abstract:

Antihypertensive agents and their use in preventing cognitive impairment have been studied. Changing practice patterns in prescribing antihypertensive medications would not be justified at this point. Sympatholytic agents increased risk. Hypertension status and/or blood pressure levels were not related to cognitive performance. The control group is entirely made up of those in the study population not taking the antihypertensive agents. Blood pressure levels have been associated with cognitive outcomes, so that would seem to be a potential confounder. The study discussed was done in a sample of older African Americans only, and hypertension is extremely common and relatively understudied in this group. More study is needed and other variables should be investigated.

Editorial

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Cognitive impairment and mortality in older primary care patients

Article Abstract:

Research on subjects 60 years of age and older indicates that moderate to severe cognition difficulties are positively correlated with a higher risk of mortality. The studies were controlled for both clinical and demographic characteristics. Further research is suggested for patients with mild cognitive impairment.

Research, Mortality, Patient outcomes, Risk factors, Cognition disorders in old age, Geriatric cognitive disorders, Old age

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