Muscle blood-flow dynamics at exercise onset: Do the limbs differ?

Article Abstract:

A review of contemporary exercise models and data acquisition and analysis techniques for evaluation of muscle blood-flow dynamics at exercise onset is presented together with a summary of the available information on exercising muscle blood-flow dynamics based on the forearm exercise model. Preliminary findings indicate that the major characteristics differentiating the limbs reflect a sensitivity of the forearm vasculature to aging and chronic obstructive pulmonary disease (COPD) that is not demonstrated by the leg vasculature.

Muscles

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Is there a difference in vascular reactivity of the arms and legs?

Article Abstract:

The lower-limb vasculature is exposed to higher hydrostatic pressures than the arms during much of the day, and study examines whether arterial reactivity differs between the upper and lower extremities of humans. Evidence suggests a pattern of functional vascular heterogeneity in human limbs, with greater blood-flow responses to physiological vasodilator stimuli generally reported in the arms of younger healthy subjects, whereas greater sympathetically mediated vasoconstrictor responsiveness is generally observed in the legs.

Arm, Leg, Extremities, Lower, Extremities, Upper

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Aging, exercise, and limb vascular heterogeneity in humans

Article Abstract:

The findings from three studies are reported with the aim of investigating between-limb vascular differences through evaluation of arm (brachial artery) and leg (common, superficial, and deep femoral arteries) limb blood flow (ultrasound Doppler) during isolated-limb-specific exercise and after postcuff occlusion hyperemia. Collectively, these studies demonstrate a significant between-limb vascular heterogeneity in humans that is influenced by age and by exercise training.

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