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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

A comprehensive genetic map of the mouse genome

Article Abstract:

A comprehensive genetic map of the mouse is presented. The five-year project produced a map containing 7,377 genetic markers that are comprised of 6,580 simple sequence length polymorphisms integrated with 797 restriction fragment length polymorphisms in mouse genes. About 0.2 centimorgans or 400 kilobases is the average spacing between genetic markers. The map concludes the first phase of the Human Genome Project, which involves the creation of genetic maps of man and of the mouse.

Author: Lander, Eric S., Page, David C., Jenkins, Nancy A., Copeland, Neal G., Daly, Mark J., Steen, Robert, Miller, Joyce, Hawkins, Trevor L., Dietrich, William F., Merchant, Mark A., Damron-Boles, Deborah, Husain, Zeeshan, Dredge, Robert, Ingalls, Kimberly A., O'Connor, Tara J., Evans, Cheryl A., DeAngelis, Margaret M., Levinson, David M., Krugiyak, Leonid, Goodman, Nathan, Stein, Lincoln
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
Genetic aspects, Mice, Mice (Rodents), Human Genome Project, Animal genetics

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Genome-wide detection and characterization of positive selection in human populations

Article Abstract:

An analysis over 3 million polymorphism from the international HapMap Project phase 2 (HapMap2) to detect positive natural selection across the human genome is reported.

Author: Lander, Eric S., Sabeti, Pardis C., McCarroll, Steven A., Xiaohui Xie, Fry, Ben, Varilly, Patrick, Lohmueller, Jason, Hostetter, Elizabeth, Cotsapas, Chris, Byrne, Elizabeth H., Gaudet, Rachelle, Schaffner, Stephen F.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Science & research, Natural selection, Population genetics, Haplotypes, Human genome

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An SNP map of the human genome generated by reduced representation shotgun sequencing

Article Abstract:

A simple method, called reduced representation shotgun sequencing, is described for use in creating single nucleotide polymorphism maps.

Author: Lander, Eric S., Altshuler, David, Pollara, Victor J., Cowles, Chris R., Van Etten, William J., Baldwin, Jennifer, Linton, Lauren
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000

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Subjects list: Research, Chromosome mapping, Genetic polymorphisms
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