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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans

Article Abstract:

Worm Caenorhabditis elegans is a model system used for many aspects of biology including studying host responses to bacterial pathogens but is not known to support replication of any virus. A new model genetic system Caenorhabditis elegans studies animal virus host interaction and indicates that mammals might use an antiviral response.

Author: R. Lu, Maduro, M., F. Li, H.W. Li, Brotiman-Maduro, G., W.X. Li, S.W. Ding
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Host-virus relationships

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Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

Article Abstract:

A study was conducted to identify all genes essential for mitotic cell division in a metazoan organism. A phenotypic profiling system was developed to show high correlation with cellar processes and biochemical pathways, thus enabling to predict new functions for previously uncharacterized genes.

Author: Jones, M., Martin, C., Hyman, A.A., Sonnichsen, B.M, Koski, L. B.M, Walsh, A.M, Marschall, P., Neumann, B., Brehm, M., Alleaume, A.M., Artelt, J., Bettencourt, P., Cassin, E., Hewitson, M., Holz, C., Khan, M., Lazik, S., Nitzsche, B., Ruer, M., Heinkel, R., Hantsch, H., Roder, M.; Finell, J., Jones, S.J.M., Piano, F., Gunsalus, K. C., Oegema, K., Gonczy, P., Coulson, A., Echeverri, C.J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Gene silencing, Systems biology

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Subjects list: Research, United States, Genetic aspects, Caenorhabditis elegans, RNA interference
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