Annotation competition spurs Drosophila sequencing efforts

Article Abstract:

Competition between rival bioinformaticists has been used to identify the most accurate computational modelling tools for locating and describing genes hidden within a sequenced genome. An immediate goal was to identify the best tools for annotating the Drosophila genome. The aim is to encourage the bioinformatics community to improve the predictive capabilities of its software tools.

Bioengineering

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Structures by numbers

Article Abstract:

Rapid progress in the fields of genome sequence data and automation mean that structural biology is now becoming structural genomics. This will change how structural biologists work, and how drugs are developed.

Innovations, Pharmaceutical industry

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A mutant mouse menagerie

Article Abstract:

Issues are presented concerning the breeding of mice with genetic mutations for use in the study of gene function. The importance of these mice to the understanding of the human genome is discussed.

Methods, Gene mutations, Gene mutation, Genetic research

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