Behavioral improvements with thalamic stimulation after severe traumatic brain injury

Article Abstract:

A 6-month double-blind alternating crossover study has shown that bilateral deep brain electrical stimulation (DBS) of the central thalamus has modulated behavioral responsiveness in a patient who has remained in minimally conscious state (MCS) for 6 years following traumatic brain injury before the intervention. The results have provided evidence that DBS can promote remarkable late functional recovery from severe traumatic brain injury.

Diagnosis, Prognosis, Brain, Volumetric analysis, Brain injuries, Clinical report

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BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration

Article Abstract:

The genes six-3 and pax-6, as well as members of the bone morphogenetic protein (BMP) pathway were tested for their ability to induce lens regeneration in newt embryo. It was found that the lens can be regenerated from the ventral iris when it is transfected with six-3 while only expression in the dorsal iris is significantly increased, which it suggests that this regeneration occurs through a gene regulatory mechanism.

Analysis, Physiological aspects, Genetic aspects, Growth, Genetic regulation, Morphogenesis, Company growth, Newts

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Gene regulation and DNA damage in the ageing human brain

Article Abstract:

The ageing of the human brain is a cause of cognitive decline in the elderly and the major risk factor for Alzheimer's disease. DNA damage is markedly increased in the promoters of genes with reduced expression in the aged cortex.

Causes of, Risk factors, Alzheimer's disease, Brain research, Cognition disorders in old age, Geriatric cognitive disorders

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