Cell death in the nervous system
Article Abstract:
The cell death pathways have helped in understanding the therapeutics of neurodegenerative disease states. Neurodegenerative diseases are found to trigger neuronal cell death through endogenous suicide pathways and although the cell death itself might occur late in the course of the degenerative process, the mediators of the underlying cell-death pathways have shown promise as potential therapeutic targets.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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Netrin-1 controls colorectal tumorigenesis by regulating apoptosis
Article Abstract:
An attempt is made to that inhibition of cell death by enforced expression of netrin-1 in mouse gastrointestinal tract leads to the spontaneous formation of hyperplastic and neoplastic lesions. Further, data is presented that demonstrate that netrin-1 can promote intestinal tumour development, probably by regulating cell survival.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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A new way to network
Article Abstract:
The nerve cell will extend into projections called axons during the development of the nervous system. The growth and growth direction of these axons are discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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