Chromatin regulates origin activity in Drosophila follicle cells
Article Abstract:
An examination is made to explore the relationship between chromatin modification and metazoan origin activity. The results suggest that epigenetic modification of chromatin contributes to differential origin usage during the developmental transition from genomic replication to amplification in Drosophila follicle cells.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain
Article Abstract:
PER expression restricted to the LNvs only restores the morning activity, whereas expression of PER in both the LNvs and LNds also restores the evening activity. The LNvs alone can generate 24 h activity rhythms in constant darkness, indicating that the morning oscillator is sufficient to drive the circadian system.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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Xpd/Ercc2 regulates CAK activity and mitotic progression
Article Abstract:
Results show that cell cycle function of cyclin-dependent kinase 7 (Cdk7) and CAK activity are negatively regulated by the transcription factor IIH component Xpd of Drosophila. Data indicate that downregulaion of Xpd results in upregulaion of mitotic CAK activity.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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