Cloning and expression of apical membrane water channel of rat kidney collecting tubule

Article Abstract:

WCH-CD is a protein which functions as a water channel of the apical membrane of the kidney collecting tubule in Xenopus. It is structurally similar to CHIP28, a water channel for the kidney proximal tubule and red blood cells. The localization of WCH-CD in the apical membrane and its effecting increased osmotic permeability in Xenopus oocytes suggests it is the vasopressin-regulated water channel responsible for transepithelial water recovery.

Physiological aspects, Fluid-electrolyte balance, Osmoregulation, Kidney tubules, Renal tubule

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The evolution of apical dominance in maize

Article Abstract:

Increases in apical dominance often accompany the domestication of crop plants, with the plant's resources concentrated in its main stem. The phenomenon is seen in domesticated maize, where apical dominance is far greater than in its wild ancestor teosinte. The cloning of teosinte branched1, a gene involved in evolutionary change in maize, shows that it both represses axillary growth and helps in the formation of the female inflorescences.

Plant genetics, Corn, Plant cytogenetics, Plant biotechnology

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Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

Article Abstract:

Inscuteable controls both spindle orientation and asymmetric localization of cell-fate determinants Prospero and Numb, in Drosophila neuroblasts. Localization of Inscuteable is found to depend on the Bazooka protein consisting of three PDZ domains. Bazooka may be the missing link between epithelial polarity and neuroblast polarity.

Drosophila, Neuroblastoma

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