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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Closing in on gamma-secretase

Article Abstract:

Protein-cleaving enzymes known as beta-secretase and gamma-secretase produce A-beta, a short amyloid peptide involved in the neurodegeneration seen in Alzheimer's disease. Research into the identity of gamma-secretase has highlighted presenilin.

Author: Strooper, Bart De
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000

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Model behavior

Article Abstract:

It is suggested that appropriate animal models can be used to test the effects of potential treatments for Alzheimer's disease.

Author: Chapman, Paul F.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Usage, Mice as laboratory animals, House mouse

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A partner for presenilin

Article Abstract:

A new protein, nicastrin, may be key to early studies of Alzheimer's disease.

Author: Schen, Dale
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Peptides

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Subjects list: Research, Alzheimer's disease
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