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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Analysis of the DNA sequence and duplication history of human chromosome 15

Article Abstract:

A detailed analysis of the duplication structure of the chromosome 15, which is one of seven human chromosomes with a high rate of segmental duplication, is presented. It demonstrates that some remaining gap in the genome sequence is probably due to structural polymorphisms between haplotypes, which might explain a significant fraction of the gaps remaining in the human genome.

Author: Butler, Jonathan, Cook, April, Garber, Manuel, Zody, Michael C., Kodira, Chinnappa D., DeArellano, Kurt, DeCaprio, David, Kamat, Asha, Sharpe, Ted, Young, Sarah K., Madan, Anup, Shizhen Qin, Xiaping Yang, Abbasi, Nissa, Dorris, Lester III, Dors, Monica, Johnson, Ericka, Jones, Charlien, Kaur, Amardeep, Locke, Devin P., Madan, Anuradha, Rounsley, Steven, Sneddon, Katherine M.B., Stewart, Sandra, Sougnez, Carrie, Stone, Sabrina M.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
Human genetics

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The DNA sequence, annotation and analysis of human chromosome 3

Article Abstract:

The sequencing and analysis of human chromosome 3 is described which is one of the largest human chromosomes, comprising of four contigs, one of which represents the longest unbroken stretch of finished DNA sequence. The chromosome is remarkable in having the lowest rate of segmental duplication in the genome.

Author: Jackson, Andrew, Metzker, Michael L., Jing Wang, Scott, Graham, Scherer, Steven E., Muzny, Donna M., Buhay, Christian J., Rui Chen, Cree, Andrew, Dugan-Rocha, Shannon, Gill, Rachel, Hawes, Alicia C., Gunaratne, Preethi, Hernandez, Judith, Hodgson, Anne V., Hume, Jennifer, Khan, Ziad Mohid, Steffen, David, Kovar-Smith, Christie, Lewis, Lora R., Lozado, Ryan J., Miner, George R., Morgan, Margaret B., Nazareth, Lynne V., Sodergren, Erica, Kaul, Rajinder, Jun Yu, Sudbrak, Ralf, Yan Ding, Xing-Shi Song, Harris, Alan R., Wei, Sharon, Wheeler, David A, Wright, Mathew W., Milosavljevic, Aleksander
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006

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Subjects list: Research, Nucleotide sequence, Base sequence, Human chromosomes
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