Dynamics of Drosophila embryonic patterning network perturbed in space and time using microfluidics

Article Abstract:

The robust network in 'Drosophila melanogaster' that compensates for variation in the Bicoid morphogen gradient is investigated using microfluidics. A demonstration that the compensation system can counteract the effect the extremely unnatural environmental conditions, a temperature step in which the anterior ad posterior halves of the embryo are developing at different temperatures and thus at different rates, is presented.

Drosophila, Embryology, Entomology

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Time, space and genomes

Article Abstract:

Genetic studies in fruitflies first showed that these homeotic (Hox) genes have a major role in producing the head-to-tail (anterior-posterior) pattern of tissues along the body axis. Evolutionary analyses have suggested that the common ancestor of bilaterally symetrical creatures probably possessed at least seven Hox genes, organized into a single complex.

Genetic aspects, Genomes, Diptera, Homeotic genes

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