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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Epithelial NEMO links innate immunity to chronic intestinal inflammation

Article Abstract:

A study was conducted to show that the transcription factor NF-[kappa]B, a master regulator of pro-inflammatory responses, functions in gut epithelial cells to control epithelial integrity and the interaction between the mucosal immune system and gut microflora. The results identified NF-[kappa]B signaling in the gut epithelium as a critical regulator of epithelial integrity and intestinal immune homeostasis.

Author: Neurath, Markus F., Pasparakis, Manolis, Nenci, Arianna, Becker, Christoph, Wullaert, Andy, Gareus, Ralph, Van Loo, Geert, Danese, Silvio, Huth, Marion, Nikolaev, Alexei, Neufert, Clemens, Madison, Blair, Gumucio, Deborah
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Intestines, Intestinal microbiology, Protein kinases

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Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity

Article Abstract:

Helicobacter pylori CagA have interacted with PAR1/MARK kinase, which plays a major role in epithelial cell polarity. Results show that PAR1 is a key target of Helicobacter pylori CagA in the disorganization of gastric epithelial architecture underlying mucosal damage, inflammation and carcinogenesis.

Author: Suzuki, Atsushi, Ohno, Shigeo, Saito, Yasuhiro, Azuma, Takeshi, Saadat, Iraj, Higashi, Hideaki, Obuse, Chikashi, Umeda, Mayumi, Murata-Kamiya, Naoko, Huaisheng Lu, Ohnishi, Naomi, Hatakeyama, Masanori
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Genetic aspects, Helicobacter pylori, Phosphotransferases, Report

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Developmental biology: A hairy situation

Article Abstract:

A critical step in hair-follicle, sweat gland or mammary gland development is the rearrangement of epithelial stem cells. Includes diagram, and discusses the importance of E-cadherin, which mediates cell-cll contacts.

Author: Barrandon, Yann
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
Physiological aspects, Hair follicles

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Subjects list: Research, Epithelial cells
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