Evolving Darwinism

Article Abstract:

The third phase in the history of evolutionary genetics is called post-post-neo-Darwinism. A study conducted by I.S. Novella and coworkers on the adaptive evolution in the RNA-based vesicular stomatatis virus shows that the genetic diversity in viruses will be high while the viruses fail to reach a plateau of fitness but rather are constantly changing. The variability factor will depend on the product of population size and genome-wide mutation rate whereas the loss of diversity is dependent on the rate of fixation which is determined by selection coefficients.

Observations, Adaptation (Biology), Evolutionary adaptation, RNA viruses

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Making selection work

Article Abstract:

Natural selection is used in the optimization of antibodies, drugs and enzymes, and in the design and processes of new molecules. The genetic alternatives are made by a mutational process causing evolution by natural selection. A forced evolution is practised, causing recombination in vitro by using primerless polymerase chain reactions mixed with randomly sheared molecules of different sequences. The mean fitness is enhanced by mutation, selection and inheritance consecutively.

Methods, Natural selection, Mutation (Biology), Mutation

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Predicting the future

Article Abstract:

Issues are presented concerning the use of the term fitness to describe the success of a genotype in its current environment. The difficulties experienced by scientists measuring fitness in the wild are discussed.

Influence, Gene mutations, Gene mutation, Environmental aspects, Genetic aspects, Genotype, Genotypes, Competition (Biology)

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