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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Good riddance to bad rubbish

Article Abstract:

Genetic evidence is provided to show that autophagy, cellular self-eating, helps to continuously dispose unwanted protein thus preventing neurodegenerative disease in animals. Further studies are needed in order to understand whether limited induction of autophagy may be beneficial especially in individuals prone to certain neurodegenerative diseases.

Author: Klionsky, Daniel J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
Health aspects, Prevention, Physiological aspects, Glycoproteins, Nervous system, Rodents, Cell culture, Neurodegenerative diseases

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Regulated self-cannibalism

Article Abstract:

When a cell is deprived of nutrients it degrades some of its own constituents to stay alive and it does this by the process of autophagy which is also known as self-eating. Autophagy is marked by the formation foautophagosomes, large vesicles, bounded by a double membrane, that sequester cytosol and organelles such as mitochondria.

Author: Klionsky, Daniel J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Analysis, Mitochondria, Cell membranes, Cytosol

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Autophagy fights disease through cellular self-digestion

Article Abstract:

Autophagy is involved in the cellular digestion and has a significant role in the control of cancer proliferation. The autophagic control of cellular apoptosis and survival is investigated.

Author: Levine, Beth, Klionsky, Daniel J., Mizushima, Nobory, Cuervo, Ana Maria
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
Research and Development in the Physical, Engineering, and Life Sciences, Research and Testing Services, Cancer & Cell R&D, Cancer research, Cancer, Cell physiology, Oncology, Experimental, Apoptosis

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Subjects list: Research
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