Leukaemia/Drosophila homology

Article Abstract:

A human complementary DNA clone, designated AML1 because it marks a subtype of acute myeloid leukemia, is the homologue of runt, one of a group of pair-rule genes that determines morphogenesis in the fly Drosophila melanogaster. The area of homology linking the Drosophila and human polypeptide sequences extends to the conserved exon/intron boundary. Further research is needed to establish AML1's effect on human development.

Homology (Biology), Acute leukemia, Promyelocytic, Acute myelocytic leukemia

---

The segment polarity network is a robust developmental module

Article Abstract:

Research is presented concerning the segment polarity genes of the fruit fly, Drosophila. Computer simulations are used to demonstrate the modular nature of segment polarity.

---

Polarization of the anterior-posterior axis of C.elegans is a microtubule-directed process

Article Abstract:

Research on polarity cues for Caenorhabditis elegans, and the role of microtubules, is examined in detail.

Caenorhabditis elegans

Similar abstracts:

• Abstracts: Effects of NF-kappa-B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasome
• Abstracts: Rice, microbes and methane. Stimulation by ammonium-based fertilizers of methane oxidation in soil around rice roots
• Abstracts: Delayed activation of the paternal genome during seed development. Neutrality or selection?
• Abstracts: ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
• Abstracts: New link in a web of human genes. In search of the tumour-suppressor functions of BRCA1 and BRCA2

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.