Abstracts - faqs.org

Abstracts

Zoology and wildlife conservation

Search abstracts:
Abstracts » Zoology and wildlife conservation

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Article Abstract:

The VKOR complex is analyzed in two heritable human diseases: combined deficiency of vitamin-K-dependent clotting factors type 2 (VKCFD2: Online Mendelian Inheritance in Man (OMIM) 607473), and resistance to coumarin-type anticoagulant drugs (warfarin resistance, WR; OMIM 122700) using linkage information from three species.

Author: Scharrer, Inge, Rost, Simone, Fregin, Andreas, Ivaskevicius, Vytautas, Conzelmann, Ernst, Hortnagel, Konstanze, Pelz, Hans-Joachim, Lappegard, Knut, Seifried, Erhard, Tuddenham, Edward G. D., Muller, Clem, Strom, Tim M., Oldenburg, Johannes
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Identification of the gene for vitamin K epoxide reductase

Article Abstract:

Identification of the gene for vitamin K epoxide reductase (VKOR) is reported based on specific inhibition of VKOR activity by a single siRNA pool. It is confirmed that MGC11276 messenger RNA encodes VKOR through its expression in insect cells and sensitivity to warfarin.

Author: Khvorova, Anastasia, Tao Li, Chun-Yun Chang, Da-Yun Jin, Pen-Jen Lin, Stafford, Darrel W.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

K is for koagulation

Article Abstract:

The importance of vitamins in medical and economic fields in the light of vitamin K is discussed. The key component of vitamin K metabolism in comparative genetic linkage studies in rats, mice and humans is identified.

Author: Sadler J. Evan
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Health aspects, Vitamin metabolism

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, United States, Warfarin, Vitamin K deficiency, Vitamin K
Similar abstracts:
  • Abstracts: The case against a massive black hole at the Galactic Centre. More on modified dynamics
  • Abstracts: Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Immigration denied
  • Abstracts: Robust habit learning in the absence of awareness and independent of the medial temporal lobe
  • Abstracts: Diclofenac residues as the cause of vulture population decline in Pakistan. Fatal medicine for vultures
  • Abstracts: Quasiparticle breakdown in a quantum spin liquid. A tale of tails. Getting to the bottom of a granular medium
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.