Neural correlates of decision variables in parietal cortex

Article Abstract:

A formal economic-mathematical approach for the physiological study of the sensory-motor process in the lateral intra-parietal area (LIP) of the macaque brain was developed. Most formal models of decision making assume that animals make decisions to either maximize the level of energy intake from differing options, or to match their levels of response to the reinforcement rates from different choices. The new model may offer a powerful alternative approach to traditional models.

Neurobiology, Macaques

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The p35/Cdk5 kinase is neuron-specific Rac effector that inhbits Pak1 activity

Article Abstract:

Cyclin-dependent kinase 5 (Cdk5) and p35 are required for neuronal migration. p35/Cdk5 kinase collect at the leading edges of axonal growth cones, regulating neurite outgrowth in cortical neurons. It is shown that p35/Cdk5 kinase co-localizes with Rac in neuronal growth cones, and links directly with Rac in a GTP-dependent way. Pak1 kinase, another Rac effector also co-localizes with p35/Cdk5 and Rac.

Axonal transport

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Shape selectivity in primate lateral intraparietal cortex

Article Abstract:

It is shown that many neurons in primate posterior parietal cortex exhibit sensory shape selectivities to simple, two-dimensional geometric shapes. Many neuronal units also exhibited major differences in delay-period activity in a delayed match-to-sample paradigm. The results suggested that units in posterior parietal cortex have an effect on the way shape features are attended to and remembered.

Behavior, Primates

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