Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism

Article Abstract:

A demonstration that in central nervous system (CNS) inflammation, neural multipotent precursor cells (NPCs) are able to promote neuroportection by maintaining undifferentiated features and exerting unexpected immune-like functions is presented. In a mouse model of chronic CNS inflammation, systematically injected adult syngeneic NPCs use constitutively activated integrins and functional chemokine receptors to selectivity enter the inflamed CNS.

United States, Care and treatment, Central nervous system diseases, Chemokine receptors

---

Massive infection and loss of memory CD4(super +) T cells in multiple tissues during acute SIV infection

Article Abstract:

Highly sensitive quantitative polymerase chain reaction (qPCR) analyzed is performed to determine which subsets of CD4(super +) T cells were infected, and to what extent virus propagated through these subsets. The effects of simian immunodeficiency virus (SIV) infection and naive and memory T-cell in blood, inguinal and mesenteric lymp nodes are evaluated for delineating changes in T-cell subsets during early acute infection.

Research and Development in the Physical, Engineering, and Life Sciences, Research and Testing Services, Viral Disease R&D, Viral research, T cells, Virus research, CD4 lymphocytes, Simian immunodeficiency virus

---

Similar abstracts:

• Abstracts: Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I. Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule
• Abstracts: Neotropical kitchen gardens as a potential research landscape for conservation biologists
• Abstracts: Courtship feeding in tree crickets increases insemination and female reproductive life span. Acoustic signalling and its relation to male mating success in sagebrush crickets
• Abstracts: Degenerin similarities. A stomatin-like protein necessary for mechanosensation in C. elegans. A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants
• Abstracts: Origin of the obliquities of the giant planets in mutual interactions in the early Solar System. Energetic neutral atoms from a trans-Europa gas torus at Jupiter

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.