Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver

Article Abstract:

Cell ablation and tissue complementation methods are used to perturb precursor cell number during the earliest stages of pancreatic and liver development, which is found to have profound effects on the final size of the pancreas. The results have shown that the size of some organs, including the pancreas, might be relatively fixed early in development and that growth factors might have a limited role in determining final size.

United States, Methods, Physiological aspects, Liver, Growth, Pancreas, Tissue engineering, Company growth

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Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

Article Abstract:

An attempt is made to show that DNA methyltransferase 3-like (Dnmt3L) is expressed in tests during a brief perinatal period in the non-dividing precursors of spermatogonial stem cells at a stage where retrotransposons undergo de novo methylation.

Science & research, Research, Analysis, Stem cells, Methyltransferases, DNA synthesis

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