Relative reward preference in primate orbitofrontal cortex

Article Abstract:

The activity of orbitofrontal neurons rises in response to reward-predicting signals, during the expectation of rewards and following the receipt of awards, according to research into the motivational properties of orbitofrontal neurons in macaque monkeys during a spatial delayed-response task. The reward discrimination took place in some orbitofrontal neurons on the basis of relative preference, not physical properties. It was established that some orbitofrontal neurons process specific aspects of motivational information.

Analysis, Brain, Brain research, Localization (Brain function)

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Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli

Article Abstract:

Two monkeys were used to record from dopamine neurons in midbrain catecholamine cell groups. Dopamine impulse responses were compared to motivationally contrasting appetitive and aversive stimuli. The aversive stimuli failed to activate dopamine neurons and induced weaker responses than appetitive stimuli. The results show that dopamine neurons are biased towards environmental stimuli with appetitive motivational value.

Neurons, Dopamine, Neural stimulation

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Dopamine responses comply with basic assumptions of formal learning theory

Article Abstract:

Research describing behavioral and neuronal learning mechanisms is presented. In particular the responses of dopamine neurons to reward predicting stimuli are investigated.

Models, Learning, Dopamine receptors, Teaching models, Clinical neuropsychology

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