Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers

Article Abstract:

The effect of the peptide GsMTx4, which is a selective inhibitor of stretch-activated cation channels (SACs) and its enantiomer enGsMTinto4 on gramicidin A (gA) channel gating, suspecting it to be a bilayer-dependent mechanism is examined. The results, which are important for interpreting channel and other membrane protein functions, are discussed as also the surprising efficacy of the D form of GsMTx4 peptide, which has important therapeutic implications.

Science & research, Peptides, Membrane proteins, Peptide separation

---

Voltage-induced membrane movement

Article Abstract:

Predictions from thermodynamics on membrane movements that can be triggered by voltage stimuli are examined in detail, with results of an experiment discussed.

Electric properties, Membranes (Biology), Thermodynamics, Electrophysiology

---

Tarantula peptide inhibits atrial fibrillation

Article Abstract:

Research into the antifibrillatory effect of a peptide from spider venom is discussed.

Health aspects, Prevention, Atrial fibrillation, Arrhythmia, Spider venom, Venom, Spider venoms, Venoms

Similar abstracts:

• Abstracts: Characterization and inhibition of a cholecystokinin-inactivating serine peptidase. High constitutive activity of native H3 receptors regulates histamine neurons in brain
• Abstracts: Trans-dominant inactivation of HTLV-1 and HIV-1 gene expression by mutation of the HTLV-1 Rex transactivator. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
• Abstracts: RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase. The short answer
• Abstracts: Representations of odours and odour mixtures visualized in the honeybee brain. Learning from a fly's memory
• Abstracts: Visible flicker from invisible patterns. Realignment of cones after cataract treatment. Orientation-selective adaptation and tilt after-effect from invisible patterns

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.