Abstracts - faqs.org

Abstracts

Zoology and wildlife conservation

Search abstracts:
Abstracts » Zoology and wildlife conservation

Resveratrol improves health and survival of mice on a high-calorie diet

Article Abstract:

A study was conducted to show that resveratrol shifts the physiology of middle-aged mice on a high-calorie diet towards that of mice on a standard diet and significantly increases their survival. Parametric analysis of gene set enrichment revealed that resveratrol opposed the effects of the high-calorie diet in 144 out of 153 significantly altered pathways which show that improving general health in mammals using small molecules is an attainable goal, and point to new approaches for treating obesity-related disorders and diseases of ageing.

Author: Puigserver, Pere, Ingram, Donald K., Boss, Olivier, Lakatta, Edward G., Sinclair, David A., Poosala, Suresh, Baur, Joseph A., Pearson, Kevin J., Price, Nathan L., Jamieson, Hamish A., Lerin, Carles, Kalra, Avash, Prabhu, Vinayakumar V., Allard, Joanne S., Lopez-Lluch, Guillermo, Lewis, Kaitlyn, Pistell, Paul J., Becker, Kevin G., Gwinn, Dana, Mingyi, Wang, Ramaswamy, Sharan, Fishbein, Kenneth W., Spencer, Richard G., Le Couteur, David, Shaw, Reuben J., Navas, Placido, de Cabo, Rafael
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
Health aspects, Care and treatment, Usage, Obesity, Observations, Transmission electron microscopes, DNA microarrays, Adenosine triphosphatase genes, ATP genes, Resveratrol

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

Article Abstract:

A study is conducted to report that serum retinol binding protein 4 (serum RBP4) is elevated in adipose tissue of adipose-Glut4 mice and that serum RBP4 levels are elevated in several insulin-resistant states in mice and humans. The results establish that the RBP4-transthyretin interaction is a new target for the development of drugs to combat insulin resistance and type 2 diabetes.

Author: Peroni, Odile D., Kahn, Barbara B., Kotani, Ko, Qin Yang, Graham, Timothy E., Mody, Nimesh, Preitner, Frederic, Zabolotny, Janice M., Quadro, Loredana
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Risk factors, Type 2 diabetes, Adipose tissues, Adipose tissue, Insulin derivatives

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Article Abstract:

Research is presented concerning the influence of the glucose transporter GLUT4 in the decreased glucose metabolism and transport in adipocytes and muscle on the development of the type 2 form of diabetes.

Author: Abel, E. Dale, Kahn, Barbara B., Peroni, Odile, Kim, Jason K., Young-Bum Kim, Boss, Olivier, Hadro, Ed, Minnemann, Timo, Shulman, Gerald I.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
Diabetes, Diabetes mellitus, Genetic aspects, Mice, Mice (Rodents), Letter to the Editor, Glucose metabolism

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, United States, Causes of, Insulin
Similar abstracts:
  • Abstracts: Residue-based control of helix shape in beta-peptide oligomers. Non-haemolytic beta-amino-acid oligomers
  • Abstracts: Alternative feeding strategies and potential disease transmission in Wisconsin white-tailed deer. Sex affects age determination and wear of molariform teeth in white-tailed deer
  • Abstracts: Temperature terrestrial vertebrate faunas in North and South America: interplay of ecology, evolution, and geography wit biodiversity
  • Abstracts: Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Sperm and mammalian polarity
  • Abstracts: The neocortex comes together. Radial mosaicism and tangential cell dispersion both contribute to mouse neocortical development
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.